Vitamin D and breast cancer
Article Sidebar
Article Details
Authors
Publication Information
Keywords
neoplasms
Abstract
Introduction. Breast cancer in Guatemala is second in frequency, surpassed only by cervical cancer1. The present study was conducted to determine the association between vitamin D levels and breast cancer in patients who attended the Hospital General San Juan de Dios. Material and Methods. Case-controls study. The total sample was of 156 patients, 52 cases and 104 controls. Medical records were reviewed to confirm the diagnosis and a blood sample was taken to determine levels of 25OHD, which were processed in the Laboratorio Clínico Popular (LABOCLIP). Results. Eight patients had optimal levels of 25 OHD, two of which (3.85 %) were cases and six (5.77%) controls, No toxic level was found. Suboptimal level was determined with an OR = 1.5 (CI 0.29-7.86) risk of developing breast cancer. The group of 66-70 years had the highest levels of vitamin 25OHD with an average of 22.01 ng/ml and for the group of 56- 65 years, a mean of 21.82 ng/ml. The higher the breast cancer stage, the lower the concentrations of vitamin 25OHD. Conclusions. Of the patients evaluated, nine of ten had suboptimal levels of 25OHD, with an average of 20.65 ng/ml in cases and 19.71 ng/ml in controls. There is an inverse trend between serum 25- OHD and stage of breast cancer.
Graph - Number of readers per month
Downloads
How to Cite
License
 |
This work is licensed under Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) |
| Copyright notice |
 |
Authors will retain their copyright and assign to the journal the right of first publication of their work, which will be simultaneously subject to a Creative Commons Attribution-Noncommercial-ShareAlike 4.0 International license (CC BY-NC-SA 4.0) that allows third parties to share the work as long as its author and its first publication in this magazine are indicated. |
|
Authors may adopt other non-exclusive license agreements for the distribution of the version of the published work (eg: deposit it in an institutional repository or publish it in a monographic volume) provided that the initial publication in this journal is indicated. |
|
Authors are allowed and recommended to disseminate their work through the internet (eg, in institutional telematic files or on their website) before and during the submission process, which can lead to interesting exchanges and increase citations of the published work. (See The effect of open access). |
| About the Creative Commons license |
|
|
You are free to: |
|
Share — copy and redistribute the material in any medium or format. |
|
Adapt — remix, transform, and build upon the material. |
|
The licensor cannot revoke these freedoms as long as you follow the license terms. |
Under the following terms: |
 |
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. |
 |
NonCommercial — You may not use the material for commercial purposes. |
 |
ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original. |
| No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits. |